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I use his Formula 1 myself for constipation and it works.

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That is very interesting indeed, GA, thank you.

The area they're all circling is this elusive gut-brain interplay that seems to be significant in so many different ways but not yet well enough understood for practical everyday applications to have emerged. E.g. I know they've known about the strong association between Crohn's and depressive neuroses for *decades*; but it's such a complicated system to investigate.

Am I hoping they'll discover a pill that will stop me being so bloody miserable?! Probably! - mea culpa!
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CM, an interesting book I've partially read is by a credentialed neuroendocrinologist, who's also a professor of biology, neurology and neurological sciences and, by courtesy, neurosurgery...not sure I understand what all this means though.

I watched a program on one of his journeys to Africa to spend time studying primates. Not the vacation I'd want for my children, but they are a dedicated family.

He wrote a book, now in its third edition, titled "Why Zebras Don't Get Ulcers." I may have quoted it elsewhere on the forum, sometime in the past. It's a fascinating approach to stress, the fight or flight syndrome and long term stressors in humans.

I'll never forget his basic comparison of why some animals don't deal with stress. They don't have mortgages to pay, jobs to go to, human predators with assault weapons to hide from, taxes to pay or the IRS to deal with. They don't have bad bosses, bad hair days, clothes to buy and wear. They don't put their offspring through orthodontics, school or college. They don't have to worry about dieting, going to the gym, botox treatments, and perming their hair. And they don't have to listen to politicians.

Zebras just look for food and water, eat, perform other bodily functions, and move on, but the stress part is to watch out for lions and other predators. Granted that being chased by a pack of lionesses (for their pride, while the males relax and watch the women do the work) is certainly stressful.

But, as he points out, once the lions have made their selection and are enjoying their meal, the zebra herd goes back to grazing. Stress over, until the next lions' feeding time.

It may sound cruel, but it's actually amusing when presented in the context in which Sopolsky writes. And following that context, he addresses the long term stresses to which we humans are subject, their chemical components and how they affect the human body. If he hasn't written since the last election, I'm sure he would include politics as a stressor.

I got lost on some of the more technical medical interactions at the basic chemical level.

But the jist of his theory (as I read it in an earlier edition) is that we humans are subject to different and longer term stresses over our lives than are animals.

When you wrote of depression, I thought of Sapolsky and his theories.
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Hm.

Several tangents later, I came across an interesting article on genetics and depression, which led me to another link, which led me to this example of what credible credentials look like. For comparison, then:

Professor Edward Bullmore MB PhD FRCP FRCPsych FMedSci trained in medicine at the University of Oxford and then at St Bartholomew’s Hospital in London. After working as a physician in London and in the University of Hong Kong, he trained as a psychiatrist at St George’s Hospital and the Bethlem Royal and Maudsley Hospitals in London, and as a clinical scientist at the Institute of Psychiatry, King’s College London. He has been a Professor of Psychiatry at the University of Cambridge since 1999 and is currently Head of the Department of Psychiatry and Director of the Wolfson Brain Imaging Centre in the Department of Clinical Neurosciences. Since 2005, he has also worked half-time for GlaxoSmithKline and is currently leading an academic-industrial partnership for the development of new anti-inflammatory drugs for depression. He is a world expert in neuroscience and mental health.

[Not sure what he was doing in Hong Kong, mind. Bit of a sabbatical, fondness for the gee-gees, courting, filthy lucre..?]

Anyway. He's written what looks like an extremely interesting book called "The Inflamed Mind." I stop short of recommending it 'cos I haven't read it yet but I think I might.
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Already I find myself coming back to this thread for its comical value. I love the creative answers.
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Perhaps Willy needs to consult an anatomical chart as well.

My first thought was a word that rhymes with roll.
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Onions work for me, or pilchards. lol
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This formula of herbal medications claims:
"STIMULATES circulation and REDUCES congestion in the brain.
INCREASES oxygen and blood flow to the brain.
SUPPORTS healthy hearing and eyesight."

The only thing that stimulates circulation is exercise. If you took this formula and laid in bed all day it wouldn't help one bit.

No herbal formula stimulates the amount of hemoglobin and therefore oxygen that gets to your brain. As for blood flow, atherosclerosis has a lot more to do with it than any herbal medication.

Healthy hearing is affected by having an intact eardrum and normal levels of cerumen. Eyesight is linked more to blood pressure and glucose control than herbals.

If you need help pooping, get a bulk-forming laxative and drink lots of water.

In summary: save your money.
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WillyB - Finally a sensible answer for you from Ahmijoy.

The first poster to answer, a bear, laughed at your question.

Then a mouse practically called you gullible.

Sorry, we are not usually this silly or rude.
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Everyone got a giggle out of your post. But I would caution you against giving or taking any sort of herbal remedies without a doctor’s specific approval. Many herbs can have disastrous side effects when combined with prescription meds.
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I have checked out Dr Schulze's website.

It continues to amaze me what people are prepared to put their faith in. Not to mention their money.

I do note that the biography section includes the good doctor's having been invited to speak at Oxford University.

My former neighbour was asked to speak there, too, a few years ago, about the Town & Country Planning Act. My neighbour was certainly an expert on planning law, being a twice-bankrupt barrack room lawyer with a forty year track record of fraud, misrepresentation and perjury who nevertheless, in that remarkable way of the true con artist, always somehow came through the revolving door first. I have to declare an interest (more accurately, a grudge): the wretched man cost us fifteen thousand quid.

I think the expression is "poacher turned gamekeeper." If researchers want to know what alternative medicine is up to it's no good asking the real doctors, is it?

It particularly tickles me when people decide the best way to get a degree is to set up your own university.

I'm as fond of herbs as the next person, by the way. Jolly useful, and decorative with it. Let's hear it for herbs.
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Tsk tsk. Surely the Formula 1 is a different product from the Brain-Herbal Blend?

I haven't myself heard of Dr Schulze or his formulae, WillyB, so can only recommend that you exercise normal caution before spending good money on it.
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I'm sorry, what you wrote made me laugh. The brain herbal sounds like it is to help your top, but is helping your bottom, too.

I'm not familiar with this herbal. Sorry. But thanks for making me laugh this early in the morning.
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