Wife with Alzheimer's dementia keeps putting on 5-6 layers on when it is 90+ degrees out and will not take anything off.

Play "You Talk Too Much" by Run DMC, catchy song from 1985

My dad has dementia and wore a polar expedition type parka indoors and outdoors almost all the time no matter what the weather. This even when he went naked for the waist down. Sometimes he would wear a wooly hat indoors as well. We just let him be as far as that went. Earlier on in his progression, he talked pretty much nonstop, only on a few certain pet topics. Later, whether due to the Seroquel and Trazodone or because he simply got worse, he went to barely saying a word and ignoring what others said to him. But he did watch TV a lot. And sometimes he would respond.

I know of another dementia sufferer who does a kind of continuous, high pitched, moan/ shriek /whistle during most of his waking hours while wandering around the house. His wife said he can understand basic sentences spoken to him, but he never responds in words. She uses earbuds or noise canceling headphones or when she really needs him to stop for a few minutes, she gives him chewing gum. I’m not sure whether that would help with you wife, or whether it would be considered a choking risk. Just thought I would share.

Go into the next room where you can still keep an eye on her but not hear the stream of chatter. Use earplugs. Use noise canceling earphones.

And get her some calming meds!

Remove most of her clothing from her closet and dresser.
Keep 2 or3 pairs of pants. about the same in blouses or shirts.
Keep items that will go together no matter what she puts on.
Quite often people as people age the circulation is not what it once was and add different medications into the mix and feeling cold is common.
hats can help.
lap blankets are wonderful. Be very careful if you use heated blankets or heating pads. Burns are common.
Polar Fleece is wonderful not only does it dry fast but it has the ability to keep you warm but not be as sweltering as layering sweaters or sweatshirts.

Now the talking....
Talk to her doctor about medication for the anxiety. this is what usually causes the non stop talking or walking or other OCD type habits that some people have.
Keep in mind that any medication that can help with this can also make her a Fall Risk. So there is a trade off.

Move her clothes to where she can’t get them. A storage unit or buy a rack with a cover and keep them in the garage or something.

only keep a few days of clothes where she can get them.

Order some noise cancelling ear phones or ear buds or foam ear plugs for yourself.

The clothing doesn’t matter. The anxiety does, it’s causing the nonstop talking and has to be upsetting for her, just as it’s tormenting you. She desperately needs medication to calm this behavior. It would be a kindness to her

Your wife needs meds stat! It's not good for HER either to be talking for 7,25 hours straight, do you not realize that? Call her doctor right away. Ativan helped my mother a lot.

And so, what is your plan?
Do you plan to continue to risk your health and sanity because your beloved has lost hers?
Do you have thoughts on next steps?

Sounds like she has some anxiety. A low dose anti-anxiety med could help curb the need to constantly talk. It would drive me crazy too! And it’s probably no fun for her either.

That aside, it sounds like you are caring for her at home. It may be time for assisted living or long term care.