Should I move or renovate existing home?

Has anyone on board had to make the decision to stay in your existing home or move to another home? My husband has Parkinson disease and dementia and other health issues. We both are 65 years old. We live in a 2 story home where all of the bedrooms are on the second floor. With his health, I feel eventually we both need to have our bedrooms on the 1st floor. He wanders at night getting up several times at night going to the bathroom. We have been comparing the cost of adding a bedroom on the 1st floor, but, it is costly. The value of the homes in my neighborhood is down due to the original owners moving out and renting out their homes, short sales of homes, foreclosure, therefore, they are not up keeping their homes. When I look at the cost of the addition, which will make the value of my home more than what the houses are selling for in my subdivision. I looking around at different houses and the thought of moving makes me uncomfortable too, to start all over again. We have been in our home for 20 years. I just wanted to see if anyone out there had to make the decision to stay in their home or move. If so, how did they decide what to do?