When loved one moans, groans, cries all day and all night. When I do a diaper change she screams to the top of her lungs. What can I do?

Id think it's time for some anti anxiety meds if she reacts this way when she's changed. You probably need some assistance as well. Home health can come by just a couple of times a week to bath her and that would help you so much.

Wow, you sure do have your hands full! Do you have any help?? If not, I realllly think you need some. This must be very hard for you to deal with day in, day out.

How long has she been moaning all the time? Have you asked the doc about it? Not sure if there's a med that helps with this kind of behavior?

Have you considered a nursing home?