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nextmonkhood Asked January 2020

What to expect from end-stage liver failure?

Hello all. I'm hoping someone might be able to give me some pointers or experience.
My dad (70) is suffering from liver failure as a consequence of stage 4 colon cancer which has metastasized to the liver. He's responded well to chemo since his diagnosis 18 months ago but started suffering liver-related complications in October (ascites, jaundice, upper gastric bleeding). One week ago today, he was told by his consultant that there's nothing more they can do for him in terms of treating the cancer, and based upon his scans and blood tests, he was given 3-6 months left to live.


Unfortunately, he's gone massively downhill in the week since. He's exhausted, sleeping a lot, his jaundice has got a lot worse, the ascites has returned, he's had diarrhea, been nauseous and vomiting, and in the last day has become confused and has been unable to eat. We initially thought he had just given up and become depressed, but his symptoms have worsened massively so there's obviously something physical - rather than purely mental - going on here. His liver is finally failing, basically.


Today, on the advice of his consultant, we took him to the emergency room. They're giving him fluids and are keeping him in hospital tonight. They did some blood tests and I'm not sure of the results other than the fact that his bilirubin levels have rocketed to 4.5mg/dl and his kidneys are also starting to fail. They also asked him whether or not he wishes to be resuscitated, should the inevitable happen at any point (he said no)


We've pretty much accepted that this is obviously not a 3-6 month prognosis at this stage but the uncertainty is really getting to me. Does anyone who's had experience in caring for someone with liver failure have any idea of how close to the end we might be? Days? Weeks? It's really hard to find any information online with regards to the final weeks/days of liver failure so I'm having trouble judging and managing my own expectations.

NeedHelpWithMom Jan 2020
So sorry for your loss. It’s very hard even if you know that a loved one is dying. Sending many hugs to you.

nextmonkhood Jan 2020
Hi all,
Just a note to say that my dad passed away 6 days after my post. He declined as expected, in hospital - sleeping more, becoming disorientated, and eventually he stopped eating/drinking, fell asleep, and passed peacefully a few days later. In retrospect, it was obvious from his symptoms that we had less than a week when he went into hospital, but it still came as quite a shock. We got a call on the Wednesday morning to say that it would be 'within a couple of days', and he passed on the Thursday afternoon.

Thank you so much for your comments. This is a hard time, but we'll get through it :)

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anonymous912123 Jan 2020
I am sorry about this, my aunt was end stage, she lived for 3 weeks, she was placed in Hospice.

NeedHelpWithMom Jan 2020
I’m so sorry. I don’t think anybody can predict an exact time. Can you speak further to the medical staff?

MargaretMcKen Jan 2020
I was thinking about you and your family. My post was mostly factual, my feelings were much stronger. I hope that things are working out as well as possible for everyone, and send you all my love and best wishes. Yours, Margaret

MargaretMcKen Jan 2020
My first husband aged 75 had liver failure/ cancer. Diagnosed in November 2018, given 6 months to live, and also given chemo and other treatment. He was told nothing more was possible in February, and he died in May 2019. Clearly things are always difficult, but this sounds fairly similar to your father’s situation. Sympathy and best wishes to all your family.

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