What is the best way to proceed with Guardianship?

I am doing fine so far. I used a certified eldercare attorney for the original petition. Providing home care was fine for the judge.
The only restrictions place on me was in the area of money. And that may vary in what the court requires.
In my case I cannot make withdrawals from her saving account with out court approval. But I can use her checking account for recurring expenses or possibly for larger expenses.
Yes the paperwork can be difficult. It gave me headaches. But I did it. Much of it is what is required by the court.
In my area, once the initial guardianship was approved, I only have an annual financial report and budget to complete. Assistance from a professional like a cpa or attorney may be advisable.
The big difference is you will have, in many cases, the support of the court for so many things that a POA will not or may not work.
Of course things can vary by state. Here the courts are usually in favor of close relatives becoming the guardian. And only if thing go array will the court step in for possible corrective action.
The only real problem I ran into was getting a block put on her savings account because the credit union did not have a department or procedure for such actions but we did eventually work out an acceptable plan and the court was agreeable to it.
The annual financial report had me sweating like a long tail cat in a room full of rocking chairs but, to my amazement, I got good comments from the judge and staff in the way I was handling everything. My blood pressure has now returned to normal and I still have my DW with me and no interference.
Now it mainly will consist of keeping records and receipts until the end of this year.

I hope this helps.

Thank you, that is reassuring.