I am an RRT, but I need more information. Lots of the newer machines are quite small and will fit in your carry on or packed luggage. As they are normally only worn at night this should be fine. If you are flying and feel you may need this on the flight that may be another issue (power, for example) Call the home care company and they may be able to assist you
If the one you have is rather bulky, talk to your sleep doctor, or the doctor who ordered your sleep study about getting a smaller one. Your insurance policy may even cover a new one if it's been a few years since you got the one you have. If you are talking about flying with it, it will fly as carryon and not count against you. They do ask that you have a doctor's note that it is yours and that it is medically necessary. I usually travel with an extension cord that will carry the power load and that way in motels I have more flexibility. in the past, I have also powered mine with an inverter when camping. Be sure you have the zipper carry bag so that you can keep all the hoses and masks and filters, etc. together.
Also, after I arrive wherever I am going to be, I buy a container of distilled water or even a bottle of drinking water for the humidifier. Hopefully, this is helpful to you. You didn't give much background info to go on. If you are flying, I wouldn't pack it in checked baggage JUST IN CASE it gets lost enroute. Carry it on board.
Set it up just as you did at home.
What kind of hassle do you anticipate?
Also, after I arrive wherever I am going to be, I buy a container of distilled water or even a bottle of drinking water for the humidifier. Hopefully, this is helpful to you. You didn't give much background info to go on. If you are flying, I wouldn't pack it in checked baggage JUST IN CASE it gets lost enroute. Carry it on board.