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Hubby has Parkinson's, and is at a stage where he will argue about anything! He is in wheelchair, and can't really get around by himself. Sleeps on & off all day in his chair. Somedays, he is so hurtful to his care taker! Hope the next stage won't be as bad! Are there any meds that can calm him down. He was a very loving caring, and this stage is very hurtful. Any and all help would be grateful.

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Talk to his doctor about all the symptoms he is having.
Parkinson's patients can be tricky to medicate as there are some typical medications that are given that can NOT be given to people with Parkinson's.
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Reply to Grandma1954
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Try Seroquel. I'm really sorry...
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Reply to peanuttyxx
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My husband has Parkinson’s disease. Diagnosed over 10 years ago but dr told him years before it was possible PD.
Generally, each stage is worse. His is more of autonomic dysfunction so all organs are being destroyed and in last year constant hospitalizations due to infections.
This year the worst one so far, I thought he was not going to make it.
But he was never mean and always rather stoic.
He sleeps more in chair as well and has about 40 other symptoms.
I am sorry. Your hubby probably will not be better.
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Reply to Evamar
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Parkinson’s is progressive but highly variable. Many people live meaningful, connected lives for years with proper support.

What to expect:

Gradual changes in movement, balance, speech, cognition, and mood
Symptoms fluctuate—good days and harder days
Medication effectiveness may change over time


What helps most:

Early and ongoing PT, OT, and speech therapy
Daily movement and rhythm-based activities
Support for caregiver strain (this is critical)


Caregiver truth:
Parkinson’s is not just a motor disease—it’s a whole-family journey. Outcomes improve when caregivers are supported, not depleted.
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Reply to BettieVicencio
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Evamar Jan 17, 2026
True about caregivers being supported.
This is horrid, horrible, cruel disease with so many unknowns.
Pt and other therapies worked until they did not.
My husband was always very active and exercised two hours per day, along with skiing, rollerblading, playing hockey and doing every marathon. He was a runner, biker, hiker.
And now he can barely go to nearest bench 30-40 steps.
I let him do whatever he prefers. I do not expect miraculously getting better.
It is best to face reality.
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Be careful. My FIL became very paranoid as his PD progressed, including vivid, frightening hallucinations. My MIL had to hold him up at the toilet and pull him up out of bed. And one day he got confused and hauled off and decked her. We moved them into assisted living not long after because she couldn’t handle the lack of sleep and physical care for him any longer, and only later heard about the punch.
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Reply to ShirleyDot
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I have not dealt with Parkinson's. The meds which help calm my agitated husband have been Depakote and/or Trazodone and/or Hydroxyzine.

My husband suffered significant brain damage from a stroke 11 years ago. He has not gotten better or worse. But he does get very anxious and frustrated. It's so sad to see this once loving, kind man become mean, uncaring, and swat away anyone who comes near enough to touch him for personal cares and vitals check.

There are some anti-anxiety meds you can try, if the doctor recommends; such as xanax or citalopram (an anti-depressant). Caution: those are habit-forming, meaning if he takes them regularly for a period of time, he will begin to crave the medication sooner and in larger doses, which can cause more anxiety.
I don't know if any of these are appropriate for Parkinsons, or if there is another medication specifically designed to manage Parkinson's symptoms. Ask the doctor.
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Reply to CaringWifeAZ
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This downward trajectory is unlikely to get better and likely to get worse.
I would understand that there comes a time when it is no longer possible for family and loved ones to render care when what is needed is several shifts of caregivers with several caregivers on each shift.

It is almost certainly time now for placement. This should be lovingly explained. There will be tears, possibly rage, and that is normal. This is a horrible loss and it is worth mourning. I am so sorry.
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Reply to AlvaDeer
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Parkinsons is generally a progressive disease, worsening with time and bringing dementia along with it. You are probably seeing dementia symptoms with your husband's hurtful behavior now. There are many medications his doctor can prescribe, including calming meds. Definitely schedule him an appointment and speak to his doctor about his ugly behavior beforehand. You can send an email in hubbys portal.

Best of luck with a difficult situation.
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Reply to lealonnie1
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