My husband diagnosed with neuroendocrine tumor primary in GI tract and mets to liver on liver biopsy 11/10/2014. Stage 4 high grade. He tried a three day course of cisplatin week of Thanksgiving and doesn't want to go through any additional rounds. He's in hospice with off-duty nursing at home. In the last week he has become combative, disoriented, and anxious most of the time. He keeps insisting he wants to go home and said our house isn't his home. He seems to be living in the past. When I walk into the room he becomes verbally abusive and if I go near him he becomes physically abusive stating I won't let him leave to go home. To put the "cherry on top" he is bipolar which the depression phase manifests in incredible anger. He's still on bipolar meds but obviously with declining liver function they aren't processing efficiently. Any suggestions or guidance?