Grandma's doctor prescribed Cipro. For some reason I decided to look up the side effects and am now nervous about giving it to her. Especially since she can't or won't tell me when something is bothering her. She is going through physical therapy and I saw that tendon detachment is a side effect of this drug. What's interesting is that I already gave Grandma her first dose about two and a half hours before bedtime and she is not sleeping well. She's making more noises than usual. It could be a coincidence, it's impossible to know. And now I just read an article where the FDA says Cipro shouldn't be used for simple UTIs. Ugh! The doctor didn't order a culture either. I suppose I should mention that the only medication Grandma takes is Xarelto. So any recommendations?