We have always had holiday dinners with family, until about 8 years ago we hosted. Now we cannot host and it is hard to get my wife out.

I hope you had a wonderful Easter!! As an alternative to going out and someone may have already mentioned this, but how about a video chat with the family on the holiday(s) you would normally visit but don't feel like leaving the house?
Our family has done this for many years as we have members all over the place. Before we all had smart phones, we would bring a laptop with us to the location and the family member(s) would connect to us that way. We would leave the laptop in a central area where they could see what was going on and everyone could "stop by" to say hello and chat. It was the next best thing to them being there.
You can do Zoom, FaceTime, Microsoft Teams, etc. on your smart phone or computer.
Absent any of that, why not just have a regular telephone call?

Imho, take care of yourself first and foremost as you've been doing, else you'll fall faint and ill and may be good to no one. If it's easier on you to stay home for holidays, then so be it. You have to make it easier on yourself and your wife.

I hope you did have a good Easter - as a Catholic, we celebrate Easter for a week of Sundays (50 days). If you didn't have your Easter last Sunday, perhaps you could still do something.
I like to think about what is really important to me and my family for holidays. Is dressing up fancy, tons of decorations and having a big meal the most important thing? Or is it time with family. Some years ago my sister-in-law passed away in December. They following year my mother-in-law passed away in December. We were all grieving and tired from traveling to the funerals, so both years I declared a "Jeans and Jammies" Christmas. No big expectations. Everyone brought a dish to eat. I didn't do a lot of decorating or use my good china. We spent time with each other and gave Christmas presents, and enjoyed the children playing with each other. My pregnant daughter-in-law loved wearing her pajamas. (I felt more comfortable in jeans.)
For a while, I told my sons to bring their families to visit my mother on separate days sometime during the holidays so she would not be overwhelmed by too many visitors. This year, my mother's dementia is so advanced that I told my sons not to bring my grandchildren for fear it would upset the children to see their great grandmother so unresponsive and unable to talk. I spent Easter with my mom so her caregivers could be with their families, but it wasn't much of an Easter for me. Maybe I will have a family meal with my sons and their families for Pentecost (May 30) if Covid allows.

Dont feel guilty. Sounds like you are doing all you can do. Your children should understand. If not then there is some other issues that arent being addressed. Just be honest and remember you are your own advocate and you have needs too.

I wonder how local your kids are to you. Given that you are feeling confined and needing your own socialization and that your wife has a hard time getting up and out, it might be best to bring family to you. I don't know how many children you have, but probably, you should set up a small visit with each on subsequent weekends. Your wife probably would enjoy several small, quieter, and simple visits so that she is experiencing enjoyment for the moment and frequently. Someone suggested pizza. Something take-out brought by the visiter would be easy and fun. These low-key visits would be enjoyable for you too. Plus, it allows your kids to see what your day-to-day life is like. Also, for your own mental health, you need to get out of the house. It is important that you establish some way for someone (family or paid help) to be with your wife so that you can get out. If your wife seems to enjoy herself at the holiday events and it is mainly the difficulty in getting her ready that is difficult, then, ask for one of your kids to stop by your place an hour or two early and help get your wife ready.