Mom has had a steady succession of UTIs in the last 6 mos. We discovered a kidney stone - which with her being on Pradaxa for A-fib, led to blood in the urine on top of the infection. We saw a Urologist and the kidney stone was pulverized/passed last month, Mom is now having her 2nd infection since the procedure. She developed the first infection after surgery and was prescribed Keflex. (Her immune system is resistant to many antibiotics due to a prior long-term prescription for Bactrim after a severe bout of pneumonia.) The infection cleared only to return on the heels of completing the prescription. I've researched this phenomenon learned that it's entirely possible that with the progression of AD, her immune system is on a steady decline and thus, this could be her "normal". I read that MD's may opt to permanently prescribe an antibiotic to keep the infection at bay and I realize that this is not ideal. However, my mom's PCP requires a sample to be cultured each time before she will prescribe an antibiotic. If antibiotics were opioids, I'd get it. But, antibiotics? If part of the normal progression involves a decline in the immune system, I am frustrated that the practice of sample, culture and then prescription has to be replayed over and over. BTW, mom is able to convey whether or not she's having symptoms and in her case, the ONLY sign of an infection is foul smelling urine. Has anyone else experienced this issue of chronic infections being treated with an ongoing use of antibiotics?