After having had a UTI my uncle began having some mental issues. The Dr. upped his Zoloft to 50 mg. The issues became worse and the Dr. has him on 75 mg Zoloft, 12.5 mg Seraquel, 10 mg. Donepezil, and .05 Atavan when he is really aggitated and that knocks him completely out where he cant function. I live 800 miles from my uncle and my sister live about 1200 miles but we talk to him often. We can tell if something is not right. Sometimes he is so wired and continues to spiral out of control and then they knock him out. I just want to find a place where he does not go way up then way down. He does not know what is going on and that ads to his episodes.