What are signs of end of life?

Hi Everyone, I am recently new to the group & I care for my husband's 94 yr old grandmother whom is living with us since November 2015. Before she moved in with us she was in independent living for 2 1/2 years. She put herself in heart failure for not taking care of herself. She has low sodium, A-Fib, dementia, & also mental issues. Daughter is 72 whom is bi-polar manic depressive. Grandma came to live with us after being treated for heart failure in November. Keep in mind we found out the dimentia & psychosis just recently which explains all the repeated patterns of many hospital trips, in & out of the doctors offices which was constant as there were many complaints of constant tiredness, back hurting, itching etc...Every time we would get one issue settled, we were back in doc's office for something else. All of this for attention...part of her compulsiveness which led into the heart failure as she refused to take care of herself, she wants a man to take care of her...a man who has vitality..she wants one who drives & is in perfect health. Prior to her heart failure, she was in pretty good shape, no major illnesses, no incontinence etc! Seriously....constant, negative complainer. Never happy, always negative. Since moving in, we have had to deal with paranoia, extreme aggression, sundowners which is really bad, spitting out her meds. She is seeing psychiatrist who put her on 150mg seroquel which I give her before sundown, 30mg Mertazapine at bedtime & .05mg clonzapam which she is chemically dependent on. Yet she is still awake & up half the night. Her blood pressure shoots up & down. This morning it was 140//79 & pulse of 97, I took it hour & half later & it went down to 93/59 with pulse of 78. I am the only person who cares for her 24/7 & she acts like she requires 24/7 help....she does not, she wants it. I have had many conversations with her & she wants to die, but she is up batting curtains, people in her room, room is lit up like an airport at night , tv blaring all night long. Night before, she was up at midnight slamming her door. She says she acts this way because she is old & dying but yet does nothing to be a part of the living. Shows no interest in anything except to complain to visiting nurse how she wants to do things, but her only interest is sleeping all day & up all night. I think her spirit is restless as her meds should be keeping her down at night but all its doing is keeping her from wandering at night, not sleeping, her agitation level is down but still meds do not seem to be making her wanting to sleep at night, Her appetite has decreased....what do I need to expect here as she will be fighting it every step of the way, but yet refuses to do anything unless there is a man....I have been observing this behavior since she moved in....we had to increase her clonzapam as she was suffering withdrawl symptoms however this is still not keeping her sleeping...her blood pressure has been fluctuating alot in the past month...running high, now running low....hospice is not on board yet...