Is it best to end the relationship? I have tried everything. She is extremely self-centered and bitter about the past--e.g., her husband dying, our parents' treatment of us, our other sister, who was the "favorite child." I cannot get her off these subjects. She calls her neighbors names such as "idiot" and "tweedle dum and tweedle dee." I have depression and she makes it worse. She won't get help, as nothing is wrong with her, as far as she's concerned. Am I fighting a losing battle?