My wife’s MS symptoms include lack of bowel movement. Sometimes not too bad, other times quite bad like we’re currently having. Last week, she hadn’t had a movement. It had been 5 days and she was miserable. She takes Colace daily, as well as Miralax on occasion, and is constantly drinking plenty of water. We play with the mix depending on her frequency. She has had times in the past where nothing works, so my cousin, an Internist, had suggested what hospitals sometimes use in severe cases, Lactulose. A few months ago, without a movement for a week she took a dose. 4 hours later, still no result. I decided to take her to the ER where she finally went after a further couple hours, (those poor nurses), I know first hand what the results are like. She is in the same situation now. She is quadriplegic so she doesn’t always know when or if she’s going and must be in a diaper. She doesn’t really use the toilet, and I don’t want her constantly using a powerful prescription laxative if we can help it. I’m looking for alternatives and appreciate any you can offer.