My wife will not sit or stand in an erect position. she is always leaning to her left. Appears to be falling, could this be permanent?

My father leaned to one side when his brain tumor was growing.

My mother with dementia leaned to one side in her wheelchair and was having small strokes.

Nobody here can accurately tell you why jour wife is always leaning to the left or if it's permanent. Have her seen by her physician for testing.

Good luck to you.

Yes. Almost certainly to do with balance and brain. I think unlikely to change. But do speak to her doc about this.

From your profile:

"I am caring for my wife Linda, who is 73 years old, living at home with alzheimer's / dementia, anxiety, and depression."

and

"I am caring for my wife Linda, who is 73 years old, living at home with alzheimer's / dementia, anxiety, and depression."

I'm so sorry you are both on this journey...everything about dementia is hard.

This could be any number of health issues: stroke, back, hip or leg pain/weakness, vertigo, to name a few. Does she complain of pain at all? Is she able to express what's going on with her body?

No one can answer if this is permanent without first knowing what is causing it. Take her to a doctor to get the answer you want.

Also take yourself for an annual wellness check and discuss the stress of caregiving. You need to make an effort to make your own needs a priority. It will feel hard, or even make you feel guilty, but it's critical that you do it.