My mother has moderate dementia & COPD. Until recently, she remained stable on a Ventolin inhaler administered with a spacer so that timing wasn't a big issue. Unfortunately, despite 4 time per day usage, that no longer works for her & she wheezed like some old steam engine. The doctor has tried Advair, Dulera & Spiriva, all of which have worked well but my mother adamantly refuses to allow refill of either script because of the monthly price... $300 range for the Advair or Spiriva & $1000 (!!) for the Dulera. I convinced her doc to prescribe a nebulized Albuterol solution thinking the longer administration time would open her up better, get the medicine deeper into her lungs & keep the shortness of breath at bay longer than just a pocket inhaler. I had explained the nebulizer to her & she agreed that she would do it & she was very pleased with the $4/mo pricing at Walmart. Now, of course, that I have everything arranged & purchased the nebulizer machine, she refuses to use the nebulizer for more than a minute or two so she's not even coming close to getting a full treatment. It's just a matter of time before the inadequate treatments catch up with her & she'll become significantly short of breath but no amount of talking, explaining, begging or even threatening will get her to complete a full treatment OR take even a partial one more than twice a day. Of course, when she becomes short of breath, that's all I hear about..."I feel so bad."..."I'm so short of breath"..."I don't understand why I'm so short of breath all of the sudden", etc. When I try to explain why, she becomes angry & denies everything I tell her as being untrue. The longer I try to convince her otherwise the angrier, NASTIER & more adamant she becomes. Any ideas on how I can get her to comply with the nebulizer?