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My 84-year-old mother has moderate dementia and is experiencing dramatic urinary incontinence. My siblings and I recognize that this is not unusual, but one did research and found that memantine (which she is currently on at what the doctor said is the highest dose) may increase incontinence. Has anyone noticed this (if there is even a way to figure it out!)? Thanks!

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The incontinence is going to be a given, as funkygrandma pointed out.
Wiith the dementia there comes a point of no return in the ability to control urination, and you may have reached that point. I remember being suprised by the changeover as well, because it seemed a bit sudden to me--even had Mom checked for a UTI, but it was just the disease progressing.
There are things you can do to work around it a little, like reducing post-dinner fluid intake, and timing any diuretics to match her 'awake' schedule better.
Was wondering if the increased urine output an issue because she isn't in incontinence briefs yet?
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Collsy May 20, 2026
Thanks, ElizabethY! Thankfully, she is in incontinence briefs (Always, with Poise pads as well at the suggestion of the AL staff). But from what you write, she may have gotten to that point of no return. My local sibling is working in just the direction you suggest re: fluid intake.
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Well you now have 3 different things that are causing your mothers incontinence...her dementia, her older age and now her medication Memantine.
Only one of those 3 can be changed and that is her medication, so perhaps it's time to talk to your mothers doctor about decreasing the dosage or change to another to see if that helps. But if the Memantine is doing what it's supposed to be doing now, you may just have to way the pros against the cons, and leave well enough alone, and deal with the increased incontinence.
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Collsy May 20, 2026
Thank you, funkygrandma59! It helped to have you pull out all three of those things. Yes, we're trying to figure out whether the Memantine is actually working - that's not clear either.
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