My father is 50 and has brain cancer. I am his only child and I am an adult. His sisters, that have not been in his life, are trying to take over his care and have him set up in her house with hospice. As his next of kin, can I get him moved to his home and care for him?

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Where were you when all the decisions were being made, do you live a great distance away? I just wonder because usually there would have been a period of acute care surrounding his diagnosis and treatment before he reached a stage where family needed to step in as your aunts have done, I don't understand why your help wasn't asked for then?
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Cassie, is he getting chemo? There's a side effect of it that's' called "chemo brain". It can cause confusing thoughts. What stage is his cancer?
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Cassie, if your Dad has some clear moments than an Attorney might allow your Dad to sign a Power of Attorney. While there, you also get a Power of Attorney for yourself.

Otherwise, if there is no Power of Attorney, you are next in line. If you are unable to take care of Dad [due to work or your own family responsibilities] then his sisters can help.

You mentioned that Dad's sisters have not been in his life. Are they that much older that Dad never got to know them growing up, or do you mean there hasn't been much communication between them in the last few years. Why is that?

By the way, where is Dad currently living? Is he in long-term-care? Do you feel you can do all the work that all the nurses and aides do to help your Dad? Spend 48 hours with him to get an idea of what is involved, and be honest with yourself as to whether you can do all the work. Does Dad's sisters feel they, too, can do all the work involved?

It might be better for Dad to remain in a continuing care facility, I assume that is where he is, and have Hospice come in to help out.
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It would take some more details to respond to your question. For whatever reason, the powers that be seem to feel that his sister is set up properly to care for him with the aid of hospice. If he is getting good care I wouldn't move him. He's going through a lot right now.
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