How do you decide to end life support when the individual is conscious?

This may not be the appropriate place for the question but I need support. My friend of 48 years went in for a routine biopsy of her pancreas 4 weeks ago. Unfortunately the doctors discovered that her bile duct was blocked. Additionally she had internal bleeding in her stomach resulting in emergency surgery and removal of a portion of her stomach. A couple of days later a drainage was input for her bile. All seemed normal and recovery underway until another episode of internal bleeding. This time it was a blood vessel in her liver which was discovered after injection of dye to locate the bleeding. This causes the kidney to take a huge hit. Long story short, kidneys are not waking up, liver not functioning, mass in her pancreas is inoperative and at age 66 my dear friend cannot handle chemo or any surgery. She is on a ventilator, has a tracheotomy, receiving dialysis and continuous morphine drip to manage the pain. She is conscious and aware of condition but has not indicated she is ready to give up. In the past she has told family and friends she does want to be kept alive by machines. Do we ask her what she wants or take her off the ventilator to see if she can breathe on her own? The family thinks it's time because there's nothing that can be done at this time for her and she is basically on life support. Should we try to ask her?