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We notice a terrible odor coming from her and think she is using only 1 depend for days.

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She should change them as soon as possible after they are wet. And if she sometimes goes whole days without wetting them they should be changed at least once a day. 

Your profile says incontinence is her only problem. If her mind is still sharp you may be able to reason with her about the medical risks of staying wet. I remember having a talk with my mother, reminding her of how careful she always was to keep all 4 of her daughters clean in that area, and now she had to do the same for herself.

If you think this is motivated by being thrifty, perhaps you can inform her of what an awesome bargain you got on them, or even that insurance is now providing them. These kinds of fibs are kind if they improve life for the patient.

How to get her to agree to this is the tough part, isn't it? Do you have scheduled times you take her to the bathroom? Always take a clean depend with you (or store them in he bathroom) and help her change anytime she is wet.

If she still smells bad after a shower, a clean undie, and clean clothes, I would definitely contact her doctor.
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It's not good to stay in wet depends for too long because sores and chafing will appear and cause her to be very uncomfortable and hurt down there and it will create more problems.I think she should change them after every time they get wet.
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Kosmo, I see that your friend is 90 years old, thus was a child of the Great Depression.   Chances are good that she is only using one Depend per day, trying to save money.  

My parents did that and their whole house had this odor.
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Get her to a doctor asap. If your baby had a terrible odor, you would call the MD would you not?
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