My sister, age 91, has extreme weight loss, muscle weakness, fatigue, confusion, no appetite. I found that she had stopped taking her Synthroid medication (thyroid was removed years ago). I managed to get her back on them a few days ago. My question: how long does it take for the meds to show some results? Plus she was taking pills at night in the past and not on an empty stomach as it should. She is on 75 mcg alternating with 62 mcg every other day. I going that resuming Synthroid will relieve her symptoms.