Are these meds for her u.t.i.? You might be able to get them in a different formulation, such as a paediatric syrup, which is more acceptable to her - or, if it comes to it and there's no way round and it's essential, easier to mix in with soft foods or with drinks.
You can also take medical advice on how essential it is that she takes them. If a break won't pose a significant risk, you can try again later and see if she feels differently then.
Do you know why she's saying no? Doesn't like the taste? Doesn't trust them (or, sadly, you)? Having trouble swallowing? Even if her "reason" isn't strictly rational, figuring out what she objects to might show you a way to persuade her.
Try to avoid confrontation or conflict - stressful for both of you, and more likely to set her against the whole idea for longer.
PS I'm assuming, here, that your wife's dementia is sufficiently advanced for her not to be competent to make medical decisions. If that's not so, then she has the right to refuse; and apart from present her with information and offer her the medication you ought not to do anything.
You can also take medical advice on how essential it is that she takes them. If a break won't pose a significant risk, you can try again later and see if she feels differently then.
Do you know why she's saying no? Doesn't like the taste? Doesn't trust them (or, sadly, you)? Having trouble swallowing? Even if her "reason" isn't strictly rational, figuring out what she objects to might show you a way to persuade her.
Try to avoid confrontation or conflict - stressful for both of you, and more likely to set her against the whole idea for longer.
PS I'm assuming, here, that your wife's dementia is sufficiently advanced for her not to be competent to make medical decisions. If that's not so, then she has the right to refuse; and apart from present her with information and offer her the medication you ought not to do anything.