My mom was diagnosed with follicular lymphoma about 6 years ago at 78 years old. She was treated with rituxin..and did ok fo a while. Then suddenly about 2 years ago she went to get up and could not move her legs. We later found she had 2 tumors on her spine which were radiated, which was successful, but it still left her predominantly wheelchair bound since then, and she now resides in a nursing home. She is niw 84 years old and had a recent pet scan which showed "progressive diffuse bone ? mets, involving ilium, pelvic bone and L-5" - bottom line, more lymphoma activity than her prior pet scan of almost 2 years ago showed. We considered a biopsy to see what, if any, treatment options there are, but her oncologist suggested waiting a few months in the absence of any other substantive symptoms and we agreed..at least at the time. He felt why take a chance with giving her any ongoing discomfort from a biopsy (either from spine or underarm), since she is feeling "relatively" well for her; and wondering if it morphed into an aggressive form of lymphoma if she would she want to be treated aggressively anyway..could she handle it, especially because she is in a wheelchair, dependent on nursing home staff for most, if not all, of her ADL? Of course, I am second guessing this approach now. I would love to hear from ANYONE who's been in a similar experience to just give me some support and guidance..doctors, caregivers, patients..anyone with something to share! Thank you!!