How to help parents re-locate with ease?

Maybe you could host a small cookout at their house and invite some neighbors, keep it small to not overwhelm mom. Maybe take a morning and escort them to senior center, stay even if they want to go and just read the paper or join in a card game, stay for lunch, this will orient them to the activities. Is there a church they could join? Dine out club? Senior center hosts a number of activities and outings. Moving to new area is hard for older parents to start over and a lot of pressure on you. Find out what they love, then introduce them to a few groups or areas to enjoy, library, etc. maybe you could volunteer together for a couple months at some place, hospital, senior living center, library, church, then once your mom starts getting comfortable and meeting a couple people, you can drop out and she can continue. Also there are "mall walkers" or daily morning walks "silver sneakers" at local YMCA. Just some ideas.

Where are your parents relocating to? Why are they moving? With a little more information more folks may be able to help you better.