My grandmas (82) depression has worsened drastically in the past month. I'm at a loss with what to do. Any advice?

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Over the past two years she's suffered a broken shoulder, knee surgery, and worsening macular degeneration. My grandparents live together but with his heart condition I've stepped in to lower his stress level. She's been depressed over the past year due to not being able to drive and just getting older. She used to paint and I'd take her shopping and out to lunch. Now I can't even get her to leave the house because shes "too tired". She's been taken to the ER three times this past year for low potassium and low sodium. Just last week my grandpa called 911 because he thought she was having a seizure. Turned out it was a massive panic attack and the doctor prescribed Celexa. Also three months ago her brother passed away. He had abused her when she was young and did get therapy for it but I think his passing triggered something. She just started to see a therapist last week which is great news. I'm concerned that a 1 hour once a week therapy session isn't enough. I also take her to acupuncture and physical therapy once a week. She spends her days watching the world news (which makes her cry) and playing candy crush. She won't listen to my requests to do other activities instead. The BIG stress in her life is my mother (her daughter). She hasn't come to terms with accepting her current relationship with her . My mother is very jealous of her and how close my sisters and I are to her and has always been rude to my grandma. My grandmas been trying to stand up to her but can't handle the idea of not talking to her. I remember yelling at my mother as a child to not yell at my grandma. My mother never listens to my requests to leave her alone and instead still talks to my grandma about her life drama and how my sisters and I are mean to her then says "dont tell the girls that I called". She also calls her house to see if my sister and I are there but never calls to see how she's doing. I've come to terms with my mother and how her behavior is toxic but my grandma can't let go. I really wish I could skip holidays and birthdays all together because of my mothers presence. All of this aside my grandma is truly a saint and all of my happy childhood memories stem from her and the love she gave my sisters and I. I don't know how we would have turned without her in our lives. I'm at a crossroads because I feel like she's giving up and I want to help. (Please note: she had a mental breakdown in her late 40's and I'm worried it could happen again) I plan on seeing a therapist to talk out my frustration and sadness. I know this is a TON of info but I'm open to any advice.

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My grandpa actually still drives and gets anything she needs. It's really just a matter of helping her through the depression... Thanks for the comment! :)
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The fact that you wrote that your grandmother is "depressed over the past year due to not being able to drive and just getting older." Right there is the trigger that it is time for her and your grandfather to move into a retirement community with other people who no longer drive and are getting older. They could make new friends and enjoy what the community has to offer. That might even help with the family drama, as now she would be too busy with other things which would be a great distraction.
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