At nite, she wakes me up every 60 minutes or so to urinate, and half the time doesnt. She does not have a UTI. Have tried vesicare, as well as a patch to slow down urine production, gabapentin, lexapro, seraquel, lunesta, xanax, tramadone, to try to have her sleep for a least four hours...gone to neurologist, urologist, gynocologist, geriatric doctor... Can anybody offer an advice... Ps ..no liquids after six pm...she has no other ailments except glucoma... Thank you!!