My brother-in-law (age 82) was diagnosed with a gioblastoma of the brain in August. After surgery, radiation treatments and chemo, tumor is growing again and they found another. Basically, it is a matter of when, not if. Within two weeks he has become aggressive, weak and barely there - in fact, he doesn't know what he is doing. The doctor thinks it has invaded his spinal column. Total personality change, walking around like a zombie, incontinent, falling etc. He can't be left alone for a minute. Sedation only works for a while, then he is up trying to find the bathroom. Catheter not an option due to aggression - would pull it out. My sister has been up with him 5 times a night for the past two months, she can't leave him alone, used to get a sitter, but now he is uncontrollable. Her daughter is helping but they are exhausted, it is a 24/7 job for someone who is strong. Hospice evaluated but won't take him because he is aggressive and over the 165 lb weight limit for the volunteers to handle. Not yet bedridden. They will have to hire an aide 3 days a week, if anyone will do it, but the rest of the time, sis is on her own. I'm afraid it is going to kill her. Medicare won't pay for nursing home (if one would take him, unless he could be sedated all the time) which means decimating savings which are needed by the surviving spouse to live on. If hospice won't take him, who will? Awful to ask, but for those of you who have experience with this - how long can a person live after reaching this level? His quality of life is gone, he was a dignified and fastidious and kind man and would be horrified if he was aware of what he is now. I'm so worried about my sister (age 79). She can't keep this up - it is going to kill her before it kills him. This is a horrible situation - the state or fed only helps if you are broke, and if you have a little saved for your retirement to live on, you have to give it all up first to get help, which leaves the spouse destitute. Any advice?