She is Bipolar depressed and I am Bipolar manic. I am prescribed Seroquel. She has been on Lithium most of her life so it is shutting down her kidneys and can no longer take it. However I know that we r at 2 opposite ends of the spectrum but she should not be given Seroquel. She says she feels worse and now I know why. She also has debilitating anxiety and the cut down her Klonopin and Trazadone. She is miserable and I thought with my poa and medical proxy that they needed my prior approval for a medication change. Am I wrong cuz we went through this once before and her Dr. always contacted me prior to a medication change.