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I think it is hard trying to prove a negative, the drugs are meant to stabilize and slow progression not reverse or cure, so how can you ever really know if they are helping?
Drug companies invest in studies that compare groups that get drugs against those that do not, and compare the groups as a whole, not as individuals, to come up with their claims of benefit.
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I hope you get some responses to your question. I have never heard many positive things about these type of medications, though, there must be cases that they do make a difference. I just never hear of them. I have read quite a few things about the side effects, but that is to be expected with any medication.
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