Mom is 90 and has been on Cymbalta for a little over a year, and it seemed to help with her fibromyalgia, but not so much with her state of mind (she has dementia). For the past two weeks she has it in her head that this drug is "bad" for her and is causing stomach upset and a "burning" throat". She stopped taking her pantoprozole three weeks ago saying it doesn't help. I put her on Nexium instead and found out she is refusing to take it. Now, she decided not to take her Cymbalta, which I know has withdrawal effects so I am trying to wean her off. I don't believe she is taking this (every other day 30mg.) and now she is vomiting, has stomach pain and is becoming very agitated. She is refusing to go to the ER and I am tired of fighting with her over everything we try to do to help her. Her PC is at a loss, because there is NO reasoning with her. This isn't entirely due to the dementia but compounded with her negative, obstinate attitude. I know she belongs in a facility better equipped to handle her, but getting her there is another issue entirely. She will not move. I guess my question is....if anyone has ideas on how to make this withdrawal more tolerable......and how do you deal with someone who refuses to help themselves?