Over the past couple years my downs syndrome brother with AZ has been experiencing seizures. He is on medication (Tegretol) which has been increased as the seizures progress. Originally they were called drop seizures but I really don't know what they are called (there are so many different kinds). The doctor explained the brain is shrinking. They always occur at bed time between 12 and 2 AM. I follow the threads here and haven't seen this discussed.