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Mom is bedridden now and increasingly unresponsive, eating and drinking very little. Since we know Seroquel is tolerated we'd like to continue using it to control agitation so she can rest comfortably. Until now she's taken it crushed and mixed with apple sauce. How can we get it into her now that swallowing probably isn't an option any more? Thank you for helping.

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If you could manage this it can be given rectally if you feel she really needs it. It's OK if you feel you can't do this. if she is not acting agitated don't worry about giving it. Call in hospice they will definitely help with anxiety and pain
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Hospice can provide medications that are drops, in the cheek or under the tongue. Call them in, it is time. Morphine is most commonly given and it is calming and helps with breathing.
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Im guessing that your Mom is on Hospice, and if not, you should definitely be looking into it, as she would undoubtedly qualify, and it would bring you an added layer of assistance in caring for her. There are other medications for anxiety that Hospice does use, that can be administered sublingually, or under the tongue, as well as pain medication as needed. I would think that at this point, it would be difficult for her to tolerate a feeding tube, and that may not be her wish otherwise. I'm so sorry this is a difficult time for your Mom, you and your family right now, my thoughts and prayers are with you!
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I would think that once someone reaches the point where they can't swallow applesauce the end must be very near. Have you consulted Hospice?
There may be other formulations available, a pharmacist is the best person to know what is available in that regard, you should also consult her doctors.
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Gigi, I'm sorry to learn of this development, and don't have any suggestions for oral administration of the pills. The only thing I can think of would be by feeding tube, but that's a major step and I'm not sure would be done at this point.

There's another alternative, but I emphasize I don't know if this is realistic or possible, and that's by injection or IV.

Is your mother still in your home? Is she on hospice? If so, and if Seroquel can be injected, perhaps a hospice nurse could handle this for you?

I'm hoping the nursing contingent here will offer opinions on this; they know more about injecting this type of medicine than I do.
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