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She has been on Morphine through pain management for a year and a half. Can using Morphine that long cause your organs to shut down?

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No her organs will not shut down. If she is working with a competent doctor then she can maintain a balance of quality of life.
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How old is your friend? How disabled is she by her pain? What other pain relief has been tried?
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Long term use leads to dependence and the need to use more and more which will affect organs as well as other issues. How long it takes probably depends on many variables. One could live through arthritis pain only to become an addict.
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