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Pill dispensers are great for seniors who don't have middle to late stage dementia. It would be a huge help if you could go over her meds with her doctor to eliminate the ones she really doesn't need.

I used to set up my mom's dispenser weekly and that worked great for a long time. The system failed after her dementia caused her to be suspicious of the pills and she wouldn't put certain ones in her mouth or she'd hoard them. Now her pills are handed to her twice a day by a medication technician in her memory care facility. Mom sometimes argues with the med tech and says "I don't recognize this pill! I'm not taking this!"
So her antipsychotic is a powder mixed into her water and she drinks it without a hassle.
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CrystalB1: Perhaps she can try cassettes.
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A pill organizer helps, if she is able to use it.
Someone else may need to fill it up weekly. And hide or take away the rest of the medications, to avoid an accidental overdose.
If you are able to use this method, with a daily phone call to remind her, "take the Thursday pills", that could work for a while.
But, it is time to start thinking long-term. If she is unable to manage this, then there is a lot more that she is unable to manage on her own.
Time to start looking into assisted living, memory care, or skilled nursing facilities.

You ask what kind of in home help you could look for.

Sadly, most home care aides are not qualified/authorized to give medications.
They can "remind" the patient to take their medications.

Unless you have the money to hire a nurse, or a trained medical assistant to administer medications, you will have to find a more creative solution.
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Oh - I forgot to mention - I use a fabric paint ( a marker would work just as well) to create a "star" on the top of every pill bottle that my husband (patient) needs to take daily. Sometimes there are short-term or trial medications which are not continued, or some medications in 2 bottles from the pharmacy. Anyway, I mark the tops of the bottles so I know which ones to set up in his daily pill organizer.

We've been dong this for many years now. I swear, I wouldn't know what day it is if it weren't for the pill organizer!
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Buy your mother an Alzheimer's Clock. Alzheimer's clocks display the time, day, month, and date. You can use it to set several medicine taking times.

https://www.amazon.com/Soobest-Dementia-Electric-Ringtones-Alzheimers/dp/B0D4Q1C1FP/ref=asc_df_B0D4Q1C1FP
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You can get prescriptions filled so that the pills come prepacked so that it is easier to take them
There are also pill boxes that have alarms so that it reminds you to take a pill and the pill can not be taken before it is time.
the "problem" with that is that someone has to be there to fill the pill box.
A caregiver can prefill pill boxes, the simple ones you can get almost anywhere. If you hire a caregiver from an agency they can not dispense meds but I am sure they can fill a weekly pill box. They can also remind a person to take a pill.
If mom needs more help than simply filling a weekly pill box it might be time to think about a caregiver that will come in daily. If she needs more help than that then it is a full time caregiver or the possibility of looking for a facility that will meet her care needs. (AL, MC, or SNF)
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my sibling puts my mothers meds together bi-weekly, problem is my mother doesn’t take them on schedule or she’ll move them around.
My mother is relocating next month & this becomes a huge issue as we need to find someone to not only ensure that her meds are put together but that she takes them on schedule for the most part. I’m going to reach out to the area on aging to see if they can provide some assistance or resources,
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Hello: For your parents medication, use a pill box for the week add the pills.
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