These episodes seem to come on quickly usually between 10 am and noon. They last anywhere from one to three days. She has a difficult time explaining how she feels but some of the common statements are that her eyes and forehead are heavy, she feels "terrible" and isn't hungry. She was hospitalized last October when it happened and had an MRI, blood work, CT scans, etc. Everything was normal. I took her to her PC another time during an episode and, again, blood work and a urine test were fine. She had a B12 shot that day which didn't do anything either. She recently had another MRI and there was no change from the previous one. I started tracking the days it happens to see if I can come up with some kind of pattern but am at a loss. It's usually about a month in between but this past time, it was only three weeks (I thought it might be a chemical reaction to hair color but ruled that out now). I also considered that it might be something with her morning pills but when it happened this time, she had forgotten to take them so I ruled that out. She's taking a number of different prescriptions but, when this started, nothing had changed for quite a long time. I'm stumped and so are the doctors. Has anyone else had experience with something like this and found an answer? I would really like to get this figured out so she can be OK!